CRISPR/Cas systems, Base editing/Prime editing/Gene Editing, Protein Engineering. Seeking a post-doctoral fellow to work on innovative protein engineering projects to develop new CRISPR/Cas-based tools for use in mammalian cells. The successful applicant will have a PhD in molecular biology or a related field (biochemistry, pharmacology, cell biology).
In addition, they will have documented proficiency (through publications) with general molecular biology techniques such as molecular cloning, PCR, western blot analysis, and a track record of research excellence. Other required skills for this position include past experience performing protein engineering and mammalian cell culture. Additional preferred but not required qualifications include previous expertise with CRISPR/Cas9 gene editing systems, next-generation DNA sequencing, and DNA damage assays.
Xenobiology, Synthetic Biology, Molecular Biology/Genetics.
Seeking a post-doctoral fellow to lead an on-going synthetic biology study investigating the use and applications of xenonucleic acids (chemically-modified nucleotides) in prokaryotes. In addition to carrying out experiments using CRISPR technology, adaptive laboratory evolution (ALE), and -omics techniques (e.g. RNA-seq), the postdoc will liaise with an international and interdisciplinary team of collaborators with expertise in machine learning/molecular modelling and synthetic organic chemistry.
The successful applicant will have a PhD in molecular biology or a related field (biochemistry, pharmacology, microbiology). In addition, they will have documented proficiency (through publications) with general molecular biology techniques such as molecular cloning, PCR, western blot analysis, and a track record of research excellence. Other required skills for this position include past experience culturing microbes (E. coli) and performing adaptive laboratory evolution (ALE) experiments with bacteria using turbidostat or chemostat methods. Additional preferred but not required qualifications include the ability to carry out next-generation DNA and RNA sequencing.
Salary: $50,000 CAD
All individuals interested in these positions must submit a CV, 2 examples of published or submitted work demonstrating aptitude in the relevant areas described, and the names and contact information for 3 references to [Please click the Apply button for the link or address] by the closing date.
Closing date: December 22, 2023 or until filled, in accordance with CUPE 3902.
Supervisor: Dr. Basil P. Hubbard, Associate Professor, Department of Pharmacology and Toxicology, Temerty Faculty of Medicine
Learn more about our research here: https://www.hubbardlab.ca
Expected date/Term: This FTE 1 position is available immediately for a 1 year term (renewable).
The normal hours of work are 40 hours per week for a full-time postdoctoral fellow (pro-rated for those holding a partial appointment) recognizing that the needs of the employee’s research and training and the needs of the supervisor’s research program may require flexibility in the performance of the employee’s duties and hours of work.
Employment as a Postdoctoral Fellow at the University of Toronto is covered by the terms of the CUPE 3902 Unit 5 Collective Agreement.
This job is posted in accordance with the CUPE 3902 Unit 5 Collective Agreement.
The University of Toronto is strongly committed to diversity within its community and especially welcomes applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, LGBTQ persons, and others who may contribute to the further diversification of ideas.