英国伯明翰大学博士后职位招聘–转录组学、群体遗传学/生理学方面
Global travel may be required as part of this role
We are seeking an outstanding postdoctoral researcher with a track record of comparative analysis of whole-genome sequencing data. You will engage in both internal and external (national and international) collaborations and will have the opportunity to gain additional expertise (and publication opportunities) in comparative transcriptomics, population genetics and comparative physiology. The successful candidate will be encouraged to seek and pursue new collaborations. Opportunities to supervise and mentor junior researchers are likely to arise during the appointment.
The candidate will be required to:
(i) understand sequence alignment algorithms for next generation sequencing,
(ii) have proven experience in NGS analysis and comparative genomics
(iii) knowledge of data visualization methods and of bioinformatics resources such as annotation tools and databases;
(iv) knowledge of methods and approaches for data integration,
(v) a strong statistical genetics background.
The Hayward “” lab is based within the School of Biosciences at UoB. Hayward leads the Biosystems and Environmental Change Theme: https://www.birmingham.ac.uk/research/activity/biosystems-environmental-change/index.aspx. The School houses a state of the art Functional Genomics Facility, which is part of a large recent investment in Next Generation Sequencing (NGS) at UoB. The University also has a high performance computing cluster (BlueBEAR, http://www.bear.bham.ac.uk ). The position with be co-supervised by Prof Pete Convey at BAS, offering access to specialist research facilities and the extensive polar library at BAS HQ in Cambridge.
This is an NSF-NERC funded project investigating insect (midge) species in the Antarctic region. Through comparative genomics, combined with comparative physiology and transcriptomics, we seek to understand how different species have adapted to this extreme environment and the potential impacts of climate change1. Molecular evidence indicates endemic insect species found on the continent (e.g. Belgica antarctica) are at least 30 million years separate from ‘sister’ species which occur throughout the sub-Antarctic and on the southern tip of South America 2. Thus, these species have survived through multiple glacial periods and been evolving in isolation. When sequenced, the genome of B. antarctica was the shortest known insect genome3, with several unique characteristics. We are now undertaking a detailed comparative genome analyses across multiple species.
- Devlin et al. (2023) Functional Ecology 36: 1949-1960
- Allegrucci, et al. (2006). Polar Biology 29: 320-326.
- Kelley et al (2014) Nature Communications 5: 4611
Main Duties
- Analyse and interpret NGS comparative genomics data
- Apply knowledge in a way which develops new intellectual understanding
- Disseminate research findings for publication, research seminars etc.
Person Specification
- BSc and PhD, or near to completion, in relevant discipline
- Postdoc experience in bioinformatics and comparative genomics is desirable
- Experience in developing and running complex workflows on large scale computer clusters
- Genetic association studies
Informal enquires can be made to Dr Scott Hayward, email: s.a.hayward@bham.ac.uk
To download the full job description and details of this position and submit an electronic application online please click on the Apply button above.
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We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working
