An opportunity has become available working at the Weatherall institute of Molecular Medicine with Prof. Graham Ogg’s research group. We are looking for a talented and highly motivated senior postdoctoral scientist to investigate the translational implications of mechanisms underlying human tissue T cell immune responses, studying CD1-reactive lipid-specific T cells in the blood and skin in order to define mechanisms of disease pathogenesis and to identify targets for future therapeutic intervention. The data will be used to characterise responses to novel antigens, as well as defining the responding T cells and TCR for future therapeutic development, including for inflammatory disease and cancer. The senior postdoc would work within these wider project activities, but with a particular focus on approaches to grow, investigate and manipulate the human antigen-specific T cells.
The successful applicant will have extensive experience and strong background in T cell immunology and growing T cell clones. A wide knowledge of immune data types including TCRs, available data repositories and existing tools specifically designed for analysing these data. And a Proven record of scientific publications in relevant subjects.
To be considered you should hold a Ph.D. and post-doctoral experience in a relevant subject and strong background in T cell immunology.
The successful candidate will conduct research in a dynamic and highly collaborative environment of an internationally leading research institute. They will advise and assist lab and other group members working on relevant projects. Contribute to manuscripts, presentation and other means of disseminating results.
They will benefit from the institute and wider university expertise in immunology, state-of-the-art technologies, computational biology, and big-data science. There will be opportunities to develop new models to explain differential responses of T cell populations during homeostasis, inflammation and cancer.
What We Offer
• Flexible working
• An excellent contributory pension scheme
• 38 days’ annual leave (including bank holidays)
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Discounted bus travel and Season Ticket travel loans
The post is full-time and fixed-term for 2 years in the first instance.
Applications for this vacancy are to be made online. You will be required to upload a supporting statement as part of your online application.
The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.
Only applications received before midday on Wednesday 2nd August 2023 can be considered.