Are you an ambitious researcher looking for your next challenge? Do you have an established background in membrane biology? Do you want to further your career in one of the UKs leading research intensive Universities?
Our laboratory investigates molecular mechanism of transport proteins and how their structure contributes to function. Transporters include those involved in human health including P-glycoprotein, which confers resistance to chemotherapy in cancer and the ABCA4 protein involved in retinal reprocessing in vision. The team also investigates prokaryotic Atm1, which is thought to be involved in efflux of heavy metals co-ordinated to organic compounds.
The laboratory is embedded within the membrane biology research pillar within the School of Biomedical Sciences. Teams in this pillar have considerable expertise in structural biology of membrane transporters and the use of structural pharmacology in drug design. We collaborate extensively with research groups across the University of Leeds to develop artificial membrane systems and with medicinal chemistry.
We are looking for an experienced membrane biologist with expertise in a variety of expression systems, protein purification and the reconstitution of transport proteins into membrane mimetics. For this role, you should have a PhD (or close to completion) in the mechanism of membrane transporters or a closely allied discipline, and expertise in chromatography systems for analytical and preparative applications using multiple solid phase technologies. The position will provide the opportunity for significant career development in structural biology and modern drug development systems.
The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.
To explore the post further or for any queries you may have, please contact:
Richard Callaghan, Head of School of Biomedical Sciences & Professor of Human Disease & Membrane Transport