Department: Barts Cancer Institute
Salary: £37,348 – £43,592 per annum (Grade 4)
Location: Charterhouse Square
Date posted: 30 May 2023
Closing date: 27 June 2023Overview
The post requires a dedicated, motivated and passionate postdoctoral research assistant who will lead this study. Applicants must have a PhD in a relevant subject and provide three good references. The study requires substantial skills in cell and molecular biology and will require in vivo testing of newly created cell-models. First author publications will provide evidence that you have experience in completing studies through to the final manuscript.
About the Project
LSG1 is a GTPase that is required for the biogenesis of the large 60S ribosomal subunit. Knockdown of LSG1 in normal human fibroblasts leads to cellular senescence and greatly impairs the growth of transformed fibroblasts (Pantazi et al. (2019) Aging Cell Aug;18(4):e12981). In this 1-year project funded by a Barts Charity Seed Grant, we will test whether LSG1 may be a therapeutic target in Squamous Cell Carcinoma (SCC) of the lung, using in vitro and in vivo approaches.
About the School/Department/Institute
The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer through innovative research in the laboratory, in patients and in populations. BCI is internationally renowned in many areas of cancer research and it combines ground-breaking basic research with the expertise of clinicians and clinician scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also committed in supporting and developing future cancer researchers through its extensive postgraduate training. It is one of six institutes within The Faculty of Medicine and Dentistry (SMD).
About Queen Mary
At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we’ve fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it’s simply ‘the right thing to do’ but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form.
We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities including an on-site nursery at the Mile End campus.
The post is based at the Charterhouse Square Campus in London. It is full time (35 hours per week), fixed term appointment for 3 years, with an expected start date of April/May 2023. The starting salary will be Grade 4, in the range of £37,348 – £43,592 per annum (pro-rata), inclusive of London Allowance.
Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.
Informal enquiries should be addressed to Andy Finch at email@example.com
Interviews are expected to be held or shortly thereafter.
The closing date for applications is 27 June 2023.