Why is aging the single greatest risk factor for dementia? What changes over time to render the brain increasingly vulnerable to proteins it has made throughout life? The Jankowsky lab seeks a Postdoctoral Associate to tackle this problem experimentally using controllable transgenic models for Alzheimer’s amyloidosis. We use genetic strategies to initiate the same neuropathology either early or late in life. Our goal is to compare how young and old glia respond to amyloid formation and whether the efficacy of therapeutic intervention differs in young and old brains. Researchers will work as part of a team combining mouse genetic engineering, viral circuit manipulation, neurohistology, and basic biochemistry to understand the causes of dementia and develop potential treatments.
The laboratory is located at the main Baylor College of Medicine campus which enjoys a vibrant and collegial scientific environment. BCM itself is located in Houston’s Texas Medical Center, a 1,000-acre complex of over 50 independent institutions within easy access. Houston is the fourth largest city in the US and is home to a diverse international population. The city offers great restaurants, a warm climate, and affordable housing.
The appointment is for an initial term of one year, with the expectation of continued support pending successful progress. The position comes with competitive salary and benefits, commensurate with experience. The start date is flexible, and applications will be reviewed on a rolling basis until the position is filled.
You can learn more about our lab and ongoing projects at our website: https://www.bcm.edu/research/labs-and-centers/faculty-labs/joanna-jankowsky-lab