Immediately available, multiple NIH funded, private foundation funded
The TCW laboratory (https://sites.bu.edu/tcwlab/) in the Department of Pharmacology, Physiology & Biophysics at Boston University Chobanian & Avedisian School of Medicine in Boston, Massachusetts is looking for highly motivated and skilled molecular and cellular biologists or stem cell biologiststo be the drivers of our efforts to translate the genetics of human AD toward therapeutic interventions.
The core program is to translate AD genetics and functional genomics into human brain cells both in vitro 2D and 3D models using human induced pluripotent stem cells (hiPSCs) both population and isogenic lines generated by CRISPR/Cas9 genome editing and in vivo (hiPSC/rodent chimera) systems in comparison with post-mortem brain. In particular, the research will focus on deciphering the molecular mechanism of major AD risk variants as well as protective variants, associated genes and identifying targeted therapeutics. The candidate will join a multidisciplinary and highly collaborative research team that includes computational geneticists, neuroscientists and pharmacologists in the departmentas well as Genome Science Institute and Center for Systems Neuroscience at Boston University.
Candidate qualifications include:
• PhD with stem cell experience for postdoctoral fellow
• MS or BA with stem cell experience for research associates
Preferred skill set
• Experienced in handling stem cells (mouse or human iPSCs, embryonic stem cells)
• Or, any cell type differentiation (2D or 3D cell cultures)
• Or, genome editing
• Or, CRISPRa/i screen
• Clear written and oral communication and detailed documentation skills
The job will be open until the position is filled.
Please send the following to Dr. Julia TCW, Assistant professor and Director at email@example.com
• Cover letter (required), CV with reference contact (required), major publications (optional), indicate your interest on projectsunder Any comments section or on the cover letter.
Submit the package to https://sites.bu.edu/tcwlab/talent-aquisition/
• 2-3 reference letters should be directly sent to the contactsbelow.
Boston University and TCW laboratory are an Equal Opportunity Employer and are committed to providing an environment of mutual respect and celebrating diversity.