美国明尼苏达大学博士后职位招聘–结构生物学、病毒学、分子生物学、计算机科学、生物化学方向

The University of Minnesota (UMN) is a public land-grant research university in the Twin Cities of Minneapolis and Saint Paul, Minnesota, United States. UMN was included in a list of Public Ivy universities. UMN faculty, alumni, and researchers have won 26 Nobel Prizes. The Institute for Molecular Virology fosters a collegial and highly interactive community of virologists, which provides a very attractive atmosphere in which to recruit new virologists to the University (Website:https://virology.umn.edu/).

Dr. Wei Zhang (Website:https://dentistry.umn.edu/faculty/wei-zhang) has been doing fundamental research on structural virology for more than 25 years and will continue to work vigorously on mechanistic studies of enveloped virus assembly and infection, two important stages of the virus life cycle. She has a deep interest in cryo-electron microscopy (cryo-EM), particularly understanding how structural information of macromolecules is preserved, transformed, detected, verified, and reconstituted via computation, and how the structural information is used in deciphering the cellular functions of macromolecules and their roles in biological processes. Her research expertise and interest were grounded in her training in physical science as an undergraduate student, her training in computer science as a graduate student, and her Ph.D. training from several key scientists in the world-renowned structural biology group at Purdue University, including Drs. Timothy Baker (Ph.D. mentor), Michael Rossmann, Richard Kuhn, and Jue Chen. 

An immediate postdoctoral research associate position is available at Dr. Wei Zhang’s laboratory at the University of Minnesota. The successful candidate will lead experimental design and execution to investigate the structural transformation of enveloped Alphavirus viruses during membrane fusion, using molecular virology, cryo-EM, single particle reconstruction, cryo-ET, subtomogram averaging, and related biochemical and biophysical methods. This collaborative project is funded by the National Institutes of Health (NIH) and aims to make breakthrough discoveries and deepen our understanding of the fundamental aspects of virus entry.

Additionally, the postdoctoral research associate will have the opportunity to participate in developing novel technologies to study virus assembly, maturation, and interactions with small molecules. The position offers the chance to work with world-class researchers in the Twin Cities through established and successful collaborations.

Required Qualifications: Candidates should have: (1) a Ph.D. in biochemistry, cell biology, microbiology, virology, structural biology, or related field; (2) published in international peer-reviewed journals. 

Preferred Qualifications: Experience protein structure determination and strong computation skills, or working with recombinant protein expression, cell culture, viruses (BSL-2) is a plus.

Science Careers地址：https://jobs.sciencecareers.org/job/640381/postdoctoral-associate-in-structural-biology/