英国利兹大学博士后职位—生物物理学/CryoEM
Research Fellow in Biophysics/CryoEM
University of Leeds
Job Description
Are you looking to apply your skills in Biophysics and CryoEM/ET to gain a new molecular understanding of the structure of amyloid aggregates and help to develop new routes to combat amyloid diseases?
We are looking for an outstanding postdoctoral research fellow to join our interdisciplinary team that is investigating how proteins aggregate into amyloid fibrils, the link between disease-relevant mutations and post-translational modifications and fibril structure, and how these aggregates perturb cells. This Wellcome-funded role is to use cryoEM/ET, supported with other biophysical and computational analyses, to understand amyloid fibril structure and dynamics. This will help to reveal the mechanisms by which disease-relevant mutations and post-translational modifications effect changes in amyloid aggregate formation and the consequences of aggregation on cellular function.
You will be based in the laboratories of Professors Sheena Radford and Neil Ranson, and work closely with other members of the amyloid team (funded by BBSRC, the Royal Society, MRC and Wellcome). You should have a PhD (or be close to completing one) in Structural Biology, Biochemistry, Biophysics or a related discipline, with extensive experience of using cryoEM backed up with other biophysical and computational methods to elucidate biological mechanisms.
Further information about the project and our recent publications is available in the additional information document.
The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.
To explore the post further or for any queries you may have, please contact:
Professor Sheena Radford, Astbury Professor of Biophysics
Tel: +44 (0)113 343 3170 | Email: s.e.radford@leeds.ac.uk
Professor Neil A Ranson, Professor of Structural Molecular Biology
Tel: +44 (0)113 343 7065 | Email: n.a.ranson@leeds.ac.uk