The Taghon lab has a long standing interest in understanding the molecular mechanisms that control human T cell development. Recently, we identified the cells that are migrating from the bone marrow towards the thymus to initiate human T cell development and obtained novel insights into the mechanisms that convert these multipotent precursors into early T cell progenitors. In the context of a granted Industrial Research Fund, we are looking for a postdoctoral scientist with strong experience in this field to further evaluate the functional impact of this molecular mechanism on human T cell precursor generation.
You will spend 100% of your time on research.
You are involved in translational research on human immune cell development with the aim of establishing novel cell therapy products.
You will perform in vitro cell cultures with human induced pluripotent stem cells and primary hematopoietic progenitor cells, including artificial thymic organoids, and evaluate the impact of various compounds on T cell precursor generation.
You will perform in vivo xenograft experiments to test T cell precursor activity.
WHAT WE ARE LOOKING FOR
You hold a thesis-based doctorate in life-sciences.
You have excellent oral and writing skills in English.
You have strong knowledge on human hematopoiesis and T cell development.
You have expertise in isolating and culturing of human hematopoietic progenitor cells and of induced pluripotent stem cells.
You have expertise in flow cytometry, both analysis and cell sorting.
You have expertise in in vitro models for generating human hematopoietic and T cell precursors, including artificial thymic organoids and stromal cocultures.
WHAT WE CAN OFFER YOU
We offer you a contract of definite duration for the period from 01/06/2022 – 31/08/2023.
Your contract will start on 1/06/2022 at the earliest.