Postdoctoral Research Assistant
NUFFIELD DEPARTMENT OF ORTHOPAEDICS, RHEUMATOLOGY AND MUSCULOSKELETAL SCIENCES (NDORMS)
Postdoctoral Research Assistant (156710)
Grade 7: £33,309 – £40,927 per annum
We are looking for a talented Postdoctoral Research Assistant who is passionate about advancing fundamental knowledge of how the immune system is organized and how it functions in health and disease to join the group of Dr Tal Arnon at the Kennedy Institute, to work within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford.
The type of questions that we aim to address include:
1) how do lymphocytes navigate to specialized niches in lymphoid and non-lymphoid tissues during steady state and in response to infection or vaccination,
2) how does this process control the differentiation and survival of these cells,
3) how do activated lymphocytes migrate to infected tissues,
4) how these events lead to the establishment of a durable immunity against infectious diseases.
In particularly, we are interested to explore these types of questions in the context of infection with influenza virus, focusing on mechanisms that promote the development, survival and function of resident memory B cells in the lung, and in the context of infection with blood pathogens, which present a life threatening risk of systemic infection.
To address these questions, we apply cutting-edge imaging techniques that allow us to directly study dynamic and tissue-specific events in real time, combined with genomic methods, to couple positional information with expression profiles and identify molecular pathways that regulate immune cell function.
•You will take responsibility for the planning, execution and analysis of high-quality research, ensuring the validity and reliability of data at all times, maintain ongoing scientific discussion with the PI and keep up-to-date knowledge of relevant publications and submit publications to high quality refereed journals. You will present work progress regularly and actively participate in group meetings and departmental seminars, as well as contribute to the smooth running of the Group’s laboratories with other scientists, technicians and students.
You must hold a relevant phD/Dphil in immunology or cell biology (or near completion) and have a very good publication record in high impact peer reviewed journals; at least one first author publication in a journal with an impact factor of 4 or above is required, preferentially in the field of immunology. You will have extensive prior experience in immunology, experience in in vivo work and perform effectively under pressure, execute complex and demanding experiments, demonstrate an excellent work ethics, and show willingness to work flexibly. Experience with advanced analysis of tissues by microscopy and cells by microscopy is desirable.
This is a fixed-term, full time position for 3 years.
Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:
•A satisfactory basic Disclosure and Barring Service check
•University security screening (eg identity checks)
The closing date for this position is 12 noon on 16th of April. You will be required to upload a CV and supporting statement as part of your online application.
To apply for this role and for further details, including the job description and selection criteria, please click on the link below: