北卡罗来纳大学教堂山分校（University of North Carolina at Chapel Hilll UNC），创建于1789年，是美国一所公立研究型大学，被誉为“公立常春藤”和“新常春藤”。
The Heinzen laboratory in the Division of Pharmacotherapy and Experimental Therapeutics, in collaboration with the Eshelman Institute for Innovation, in the Eshelman School of Pharmacy at the University of North Carolina at Chapel Hill is looking to immediately fill multiple postdoctoral fellowship positions to study the genetic and genomic bases of epilepsy conditions with a particular focus on somatic, brain-tissue specific genetic variants mediating seizures. The successful candidate will be part of a highly interdisciplinary environment that seeks to identify and functionally characterize genetic variants in epilepsy in order to identify novel treatment approaches in epilepsy.
The successful candidate will optimize and implement cutting-edge genomic analyses, including but not limited to long-read sequencing, whole genome sequencing, single cell sequencing, and duplex sequencing to detect somatic and germline genetic variants mutations brain tissue specimens responsible for epilepsy. The fellow will also be tasked with developing novel approaches to analyzing the genomic data generated. Depending on expertise and interest, the applicant could also have opportunities functionally or genomically characterize epilepsy associated variants in vitro in cellular models or human tissue, and/or work with the Drug Discovery Initiative led by the Eshelman Institute of Innovation to develop methods to facilitate the discovery of novel treatment approaches in epilepsy.
The ultimate goal is for postdoctoral fellows to develop specialized skill sets to drive independent research programs that can launch independent research careers.
The position requires a Ph.D. in human genetics, bioinformatics, computational biology, or related field, experience analyzing next-generation sequencing , and a publication record demonstrating research productivity.
Qualifications and Experience:
Excellent communication, organization, writing, and willingness to be part of collaborative team science is also essential.