Postdoctoral Fellow in Functional Genomics/Glycomics
The University of British Columbia
Summary of Position
The Wisnovsky lab is inviting applications for a postdoctoral research position. The successful candidate will work on several interconnected projects that apply cutting-edge CRISPR genomic screening techniques to map pathways regulating aberrant glycosylation in cancer. In addition to research responsibilities, the successful candidate will be expected to take on a leadership role in mentoring undergraduate and graduate-level researchers. We provide a supportive, dynamic research environment with strong opportunities for professional growth, project leadership and collaboration. Funding is guaranteed for at least two years with possibility of renewal.
The Wisnovsky Lab
The Wisnovsky lab (wisnovskylab.ca) is based at UBC in the Faculty of Pharmaceutical Sciences. Our group studies the cell-surface glycome, a dense network of sugar molecules that coats the surface of every living cell. The glycome plays a fundamental role in regulating the activity of our immune system, helping immune cells to distinguish normal, healthy cells from abnormal cells and invading pathogens. In diseases like cancer, the structure of the cell-surface glycome becomes profoundly altered, allowing tumour cells to escape immune detection. We apply CRISPR genomic screening technologies to better understand the complex genetic mechanisms that regulate these changes in cellular glycosylation. The overarching goal of our research is to identify druggable pathways that can be targeted to modulate glycosylation, generating new therapeutic options for the treatment of cancer and autoimmune disease.
• Ph.D. in biochemistry, cell biology, molecular genetics or a related field.
• Extensive prior experience with human cell culture and basic molecular biology techniques is an absolute requirement.
• Candidates with experience in pooled CRISPR/shRNA screening, next-generation sequencing, fluorescence-activated cell sorting, and/or primary immune cell culture are strongly preferred.
• The successful candidate is also expected to maintain a collaborative, collegial attitude towards team members of all experience levels.
How To Apply
Prospective candidates should send a cover letter, CV and contact information for three references to firstname.lastname@example.org. This position will remain open until a suitable candidate is found. No telephone calls or drop-in inquiries are accepted. Follow-up interviews will be conducted over Zoom. Only those under consideration will be contacted for follow-up interviews. The approximate desired start date is January 1, 2022 but can be flexible for the right candidate.
This posting is for the UBC Vancouver campus in British Columbia, Canada.
Please refer to reference number NC-55309 during correspondence about this position. Please visit the researcher profile of the supervisor for this position to learn more about their research.
Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.
The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world. Since 1915, UBC’s entrepreneurial spirit has embraced innovation and challenged the status quo. UBC encourages its students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.
Postdoctoral Fellows at UBC Vancouver
UBC is home to over 900 postdocs spanning all faculties and units across two campuses and a variety of affiliated hospitals, research centres, and sites, providing unparalleled opportunities to learn, discover and contribute in one’s own way. UBC’s Postdoctoral Fellows Office (PDFO) is committed to supporting the lives and career aspirations of our Postdocs, with the goal of enriching their experience at UBC and preparing them for the future. In addition to providing support and advocacy for all postdocs, the PDFO is dedicated to providing professional development opportunities that foster the development of soft skills needed in today’s professional environments, helping them secure future careers in their chosen fields.
About UBC’s Faculty of Pharmaceutical Sciences
Graduate students and postdoctoral fellows at UBC’s Faculty of Pharmaceutical Sciences work at the exciting and ever-expanding edges of the field of pharmacy and pharmaceutical sciences. This includes conducting precedent-setting research with real and tangible impact in areas such as discovering and developing new drugs, improving the quality of patient care and treatment outcomes, and developing the practice of pharmacy. Ranked #18 worldwide and #2 in Canada (2020 QS World University Rankings, Pharmacy & Pharmacology) the Faculty’s research focuses on four themes: health outcomes, molecular & systems pharmacology, nanomedicine, and pharmacy education.
Vancouver is a dynamic, cosmopolitan and progressive city, consistently ranked as one of the top cities to live in the world. Canada’s third largest city has it all: sea, parks, mountains, beaches, and four seasons per year, including beautiful summers and mild, wet winters with snow in the mountains. It’s the perfect backdrop to your academic research.