Postdoctoral Research Scientist
Cancer Research UK
Computational Biologist – multiomics analysis of heterogeneous gene expression in tumours
Initial 3 year fixed term contract with possible 2 year extension.
Would you like to develop your scientific career in a research institute that is founded on the quality of its people, acknowledged for its collaborative environment and designed to promote the development of the most outstanding and dedicated scientists? Many early career researchers have already made that decision and at present over 100 of them are now benefiting from our excellent training programme.
The Cancer Research UK Beatson Institute supports cutting edge research into the molecular mechanisms of cancer development and is one of the leading research institutes in Europe. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies, with special emphasis on imaging, metabolomics, and in vivo models.
Our innovative and ambitious research themes focus on understanding the regulation of the tumour microenvironment and cancer metabolism, in particular:
Intrinsic cancer cell vulnerabilities
Interplay between the tumour microenvironment, metastasis and recurrence
Biology of early disease, aimed at developing a ‘Precision Prevention’ approach
The Computational Biology laboratory is interested in the processes that act following transcription to regulate protein expression. The group uses machine learning approaches to develop integrated multi-omics models of the systems that control gene expression, and to understand how these processes change according to cellular context.
A postdoctoral position is available within the group to develop complex models of gene expression across tissues. This will involve working with a combination of spatial transcriptomics and imaging data, proteomics, DNA-, RNA-, metabolomics, and single cell RNA sequencing data.