剑桥大学（University of Cambridge；勋衔：Cantab），是一所世界顶尖的公立研究型大学，采用书院联邦制，坐落于英国剑桥。其与牛津大学并称为牛剑，是罗素大学集团成员，被誉为“金三角名校”和“G5超级精英大学”。剑桥大学是英语世界中第二古老的大学，前身是一个于1209年成立的学者协会。

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The Wellcome – Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/).

The lab of Dr Joo-Hyeon Lee (https://www.stemcells.cam.ac.uk/people/pi/lee) asks fundamental questions involving how stem cells sense environmental changes and determine their cell fate, and how niches develop and remodel the local environment during lung regeneration and the early stages of disease progression (Ombrato et al. Nature 2019; Choi et al. Cell Stem Cell 2020; Youk et al. Cell Stem Cell 2020; Yum et al. Nature 2021; Choi et al. Nature Cell Biol. 2021).

We are seeking enthusiastic and dedicated Postdoctoral Fellows/Visiting scholar/Research Associates to investigate mechanisms that lead to cellular reprogramming and lineage plasticity in lung regeneration and disease state. 

The successful candidates will benefit from exciting preliminary findings and highly innovative experimental model systems (e.g. novel genetic mouse models, ex vivo mouse and patient-derived human lung organoids, single cell based platforms, high-resolution imaging platforms, biophysical modelling, etc.) enabling functional interrogation of cell fates and states during regeneration and disease progression including lung cancer and fibrosis. Strong background in molecular, development and stem cell biology would be highly desirable. 

Expertise in mouse genetic models is essential for this post. Experience in primary cell cultures, flow cytometry, and computational analysis would be an advantage, but not a prerequisite. Candidates will work closely with lab members and collaborators to ensure the quality of our work.

Appointment at Research Associate level is dependent on having a PhD, an equivalent research doctorate. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once PhD has been awarded.

Informal enquiries should be addressed to Dr Joo-Hyeon Lee at jhl62@cam.ac.uk. Start date is flexible but can be as early as March 2022.

To apply please follow Post-doctoral or visiting scholarResearch Associate x 2 (Fixed Term) Job Opportunities University of Cambridge.

The closing date for all applications is Monday 31 January 2022 with interviews to be confirmed at a later date.

Fixed-term: The funds for this post are available for 36 months in the first instance.

Please upload your Curriculum Vitae (CV) with the contact information of three referees, and a cover letter describing your research interests in Lee Lab in the Upload section of the online application to supplement your application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference PS28154 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.