德州大学安德森癌症中心（University of Texas MD Anderson Cancer Center，UT MDA）是全球著名癌症研究和治疗机构，始建于1941年，是世界公认的权威的肿瘤专科医院，是美国最早的三个综合癌症中心之一，连续30年被《美国新闻与世界报道》评为“癌症护理最好的医院” ，“全美最佳癌症治疗医院”，每年治疗超10万人。

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Department of Cancer Biology, MD Anderson Cancer Center

The Jian Hu laboratory at MD Anderson Cancer Center is seeking outstanding and motivated postdoctoral or visiting scholar candidates to expand our work on molecular mechanisms underpinning brain tumor development and glia functions (Hu J., et al., Cell 2012; Shingu T., et al., Nature Genetics 2017; Zhou X., et al., JCI 2020, Ren J., et al., JEM 2021, Shin S., et al., Nature Communications 2021, Zhou X., eLife 2021).

We are particularly interested in strengthening three aspects of our research.

The first is to decipher the mechanisms of how glioma stem cells (GSCs) manage to sustain their self-renewal capacity in the sub-optimal environment outside the niches, particularly during the process of invasion and migration.

The second is to fill the knowledge gap of how glioma associated microglia/macrophages (GAMs) are converted from the antitumor to pro-tumor state and develop rational immunotherapeutic interventions to reverse immune-suppressive, tumor-promoting polarization of GAMs.

Lastly, we are looking for new therapeutic approaches for demyelinating diseases such as multiple sclerosis and chemotherapy-induced neurological defects (chemo-brain).

Qualified candidates should have strong background in one or more of the following areas: neuroscience, cancer biology, neuroimmunology, metabolism, genetics, or biochemistry. We are only interested in the candidates who are committed to ask fundamentally important questions and are fearless in trying novel approaches.

A track record of excellent first author publication during PhD training is essential. The pay scale follows NIH guidelines ($53,760 for fresh PhD with adjustment for more senior candidates).

MD Anderson is the number one cancer center in cancer care in the United States by the U.S. News and World Report’s “America’s Best Hospitals” survey.

It ranks 1st in the number of awarded grants from National Cancer Institute. It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest biomedical center. MD Anderson is an equal opportunity/affirmative action employer. Houston is the 4th largest city in the United States with relatively low living cost and no state or city income tax.

The interested candidates should send a CV to jhu3@mdanderson.org.

Jian Hu, Ph. D.

Associate Professor

Department of Cancer Biology

Brain Tumor Center

Program of Cancer Biology

Program of Neuroscience

The University of Texas Graduate School of Biomedical Science

The University of Texas MD Anderson Cancer Center

1515 Holcombe Blvd

Houston, TX 77030

https://www.mdanderson.org/research/departments-labs-institutes/labs/hu-laboratory.html