The position will have an academic appointment in the Division of Pharmacotherapy and Experimental Therapeutics.
Duties will include, but are not limited to: Defining a well-developed virtual population within GastroPlus for PBPK modeling for NAFLD/NASH patients but could expand into other disease areas.
Validate population differences through development of GastroPlus PBPK models for five (5) compounds; draft journal manuscript(s) in collaboration with Simulations Plus.
Develop, update, and/or iterate existing DILIsym software sub-models such as those for cholestatic liver injury and bile acid-mediated liver injury and/or adaptation to liver injury through a variety of modes of action.
Educational Requirements ：
PhD or a visiting scholar other relevant doctoral degree in the Pharmaceutical Sciences, Pharmacology, Toxicology, or a closely related discipline.
Qualifications and Experience ：
A strong background in pharmacokinetic and pharmacodynamic principles is required. The ideal candidate will have experience in Pharmacometrics and the modelling of data, as well as familiarity with the required software.
Equal Opportunity Employer ：
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
Position could include exposure to lab animals, human hepatocytes, adenoviral vector, and radiolabeled BSL-2 compounds as the fellow works with other members of the research team to ensure the accuracy of the model(s).
Posting Contact Information：
Department Contact Name and Title：
Nicole Kenney, HR Consultant
Department Contact Telephone or Email：
Postdoctoral Affairs Contact Information：
If you experience any problems accessing the system or have questions about the application process, please contact the University’s Equal Employment Opportunity office at (919)-962-1091 or send an email to firstname.lastname@example.org.
Please note: The Equal Employment Opportunity office will not be able to provide specific updates regarding position or application
美国北卡罗来纳大学教堂山分校（University ofNorth Carolina at Chapel Hill，简称UNC），创建于1789年，是美国历史上第一所公立大学，也是北卡罗来纳大学系统的旗舰机构。根据U.S.News最新的2015大学排名，该校是当前美国最顶尖的五所公立大学之一，同时是“公立常春藤”最初的8所大学之一，“新常春藤”联盟的25所学校之一。
北卡罗来纳大学教堂山分校的医学与公共卫生领域学科享有极高的学术声誉，六位诺贝尔生理学或医学奖获得者，以及美国国立卫生研究院（NIH）现任院长Francis Collins均为该校校友。根据U.S. NEWS或者QS世界大学排名 2015年评选中，Gillings公共卫生学院与哈佛公卫并列全美第2。牙医学院整体排名全美第3，Eshelman药学院排名全美第1, 医学院 – primary care 排名全美第2，医学研究排名全美第22。