Multiple fellow positions are immediately available in Dr. Zhenyu Zhong’s lab at the Department of Immunology, University of Texas Southwestern Medical Center (https://www.utsouthwestern.edu/labs/zhong-zhenyu/).
Our research centers at uncovering the fundamental molecular mechanisms by which inflammation is initiated, propagated and terminated when no longer needed (see examples of our recent work: Nature. 2018 Aug;560(7717):198-203; Cell. 2016 Feb 25;164(5):896-910; Nat Commun. 2017 Apr 11;8:15004; Cell. 2016 Jul 14;166(2):288-298; Nat Immunol. 2017 Jul 19;18(8):861-869; Trends in Immunology. 2019 Dec;40(12):1120-1133).
By utilizing a combination of biochemical, genetic, molecular, immunological, live-imaging and histological tools as well as single-cell “omics” approaches, we aim to decipher the multifaceted roles of mitochondria in innate immunity.
Currently, we focus on understanding how mitochondria sense loss of cellular homeostasis, and transmit stress signals to the rest of the cell (e.g. cytoplasm, ER and nucleus) to ultimately induce immune activation.
Additionally, we are also interested in understanding how common disease risk factors (e.g. aging and dietary obesity) affect mitochondrial signaling, thereby permitting onset of chronic inflammation that accelerates disease progression.
We are looking to recruit multiple talented fellows with research experience in immunology, cell biology, biochemistry and/or cancer biology.
Potential candidates should have a visiting scholar or a Ph.D. or M.D/Ph.D degree in a related biomedical field.
Women and underrepresented minorities in academia are strongly encouraged to apply. If interested, please send CV and three reference letters to email@example.com