芝加哥大学（The University of Chicago），简称“芝大”（UChicago），位于美国国际金融中心芝加哥，是世界顶尖私立研究型大学，常年位列各大世界大学排行榜前十。该校诞生了芝加哥经济学派等众多著名的芝加哥学派，创立了法律经济学，是经济学、法学、社会学等学科的世界级学术重镇。
We are seeking Postdoctoral Fellows interested in B cell/antibody mediated immunity to viral pathogens including influenza and SARS-CoV-2.
The positions will involve studies of B lymphocyte and antibody responses to influenza and/or the SARS-CoV-2 viruses.
Coronavirus: The COVID-19 pandemic continues to infect massive numbers of people making it a high-priority pathogen.
Control of the current coronavirus outbreak and avoidance of future pandemics is a critical and timely endeavor.
By understanding the underlying B cell response, antibodiesinduced, and epitopes targeted we can advance understanding of immunity to emerging pathogens and improve vaccination strategies and therapies.
Influenza: A truly universal vaccination strategy against influenza must manage escape mutations by the virus and the evolution of antibody responses to and away from epitopes that differ in their protectiveness and durability.
A successful vaccine aims to minimize viral escape by boosting responses to multiple conserved, protective epitopes.
Concepts for the broad and permanent protection against influenza variants and pandemic threats can also be applied to control the current coronavirus pandemic and avoid future pandemics.
The position will involve use of technologies such as flow cytometry, single-cell transcriptomics (i.e., 10x Genomics technology), plus generation and characterization of human monoclonal antibodies in order to understand the biology of Bcell responses to better understand immunity and inform on vaccine design.
We also have interest in novel vaccine antigen development and antibody-based therapeutic candidates. These positions will jointly provide understanding of the basic biological basis of B cell immunity to influenza and coronavirus while being simultaneously translatable to the clinic.
Candidates should have completed a doctorate level degree and have a strong background in vaccinology and/or immunology,preferably related to B cells and antibodies.
The successful candidate should have documented success in research including publications in international journals on relevant topics.
Compensation is dependent upon qualifications. The University provides a generous package of fringe benefits.
Applicants should submit an application package that includes a cover letter, CV, relevant prior publications, and contact information for three references to Patrick Wilson, at firstname.lastname@example.org.
Application review will begin immediately and continue until the positions are filled.